Bleed and the safe area
The printer's knife takes a sliver; the question is whether you planned for it.

The zone between ink and loss
A bleed is ink that runs beyond the page edge on purpose. When a press sheet is trimmed to its final size, the cut is never perfectly placed — small mechanical shifts of a millimetre or two are routine, and the bleed exists to absorb them. An image designed to fill the page to its edge must be drawn three millimetres wider on every side that will be cut. Those extra millimetres disappear. If the art stops at the intended trim line and the knife lands two millimetres early, a white strip of unprinted paper appears down the edge of the page — the press equivalent of leaving your work unfinished.
So the page has three zones, stacked like nested rectangles. The outermost is the bleed area: art extends here but will almost certainly be cut away. The middle is the trim line, where the knife is aimed. The innermost is the safe area, also called the live area — the zone in which nothing critical should be placed. Text, faces, a figure's hand, anything the reader must see: it lives inside that inner margin, typically a further three to five millimetres back from the trim line. The logic is the same as the bleed, running the other direction. If the knife lands a little too far in, nothing essential is shaved away.
For a cartoonist working in a standard digest format or a European album, the practical consequence is this: your page file is set up larger than the finished page, bleed added on the outside; and your lettering, your borders, anything load-bearing is pulled back from the trim edge by the safe margin. A panel whose art runs to the physical edge of the paper is a borderless panel — a bleed panel — and it is drawn deliberately to an oversized boundary, trusting the trim to eat what it should.

The distinction between a bleed panel and a framed one is not merely technical; it changes how the reader's eye leaves the image. A bleed panel expands outward with no interruption. A framed panel holds the reader inside its border. Both choices are compositional. Imposition fixes which edges are actually trimmed and which are folded into the spine, so knowing your page position in the signature tells you which sides of the art need bleed at all — inner margins fold, they don't cut.
Setting up the artboard correctly at the start costs nothing. Discovering the safe area was ignored costs a reprint.
